A statistician can 'weight' a result accordingly and I'd bet a wad of money that you still could not alter the yes vote affirmative anyway!!!! That's precisely why the Madrid govt have blocked any move for a referendum and suppressed the opinion poll info on the vote being in favour of self-determination. Their officials even tried to poo poo the Scottish referendum and the authenticity of poss EU referendum for one main reason and that was because of a similar simmering political situation in Catalonia where I've recently discovered a lotta reference by Catalans and local media to the similar quest for independence by a significant proportion of voting people in Scotland.